Acetazolamide
medication Under reviewA carbonic anhydrase inhibitor medication used to treat glaucoma, altitude sickness, epilepsy, and fluid retention.
Research summary
Scientific evidence from randomized controlled trials in healthy humans primarily supports acetazolamide's role in preventing acute mountain sickness and mitigating high-altitude physiological impairments during ascent. Studies demonstrate improvements in ventilation, tissue oxygenation, visuomotor performance, and pulmonary hemodynamics at simulated or real high altitudes, with consistent prophylactic benefits at doses of 125-375 mg daily. Consensus indicates it optimizes brain oxygenation and reduces inflammation markers under hypoxic conditions, though effects on baseline healthy states without altitude exposure remain limited.
Reported Benefits
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The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude
Not specified in available data
Acetazolamide during acute hypoxia improves tissue oxygenation in the human brain.
Not specified in available data
Sickness Evaluation at Altitude With Acetazolamide at Relative Doses
Not specified in available data
Drug Controls High-altitude Illness
Marc J. Poulin et al.
Visuomotor performance at high altitude in COPD patients. Randomized placebo-controlled trial of acetazolamide.
Not specified in available data
Effect of Acetazolamide on Pulmonary Hemodynamics and Right Ventricular Function in Healthy Subjects
Not specified in available data
No reports yet
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Acetazolamide during acute hypoxia improves tissue oxygenation in the human brain.
Not specified in available data
Drug Controls High-altitude Illness
Marc J. Poulin et al.
No reports yet
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Add Acetazolamide to your stack to report effects
Visuomotor performance at high altitude in COPD patients. Randomized placebo-controlled trial of acetazolamide.
Not specified in available data
No reports yet
Be the first to report this effect and help the community.
Add Acetazolamide to your stack to report effects
The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude
Not specified in available data
No side effects tracked yet
No side effects have been reported by studies or users for this habit yet.
Research (6 studies)
Effect of Acetazolamide on Pulmonary Hemodynamics and Right Ventricular Function in Healthy Subjects
Not specified in available data
The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude
Not specified in available data
Visuomotor performance at high altitude in COPD patients. Randomized placebo-controlled trial of acetazolamide.
Not specified in available data
Sickness Evaluation at Altitude With Acetazolamide at Relative Doses
Not specified in available data
Acetazolamide during acute hypoxia improves tissue oxygenation in the human brain.
Not specified in available data
Drug Controls High-altitude Illness
Marc J. Poulin et al.
Community updates
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