Research Hub

Research revealed that gut microbes produce short-chain fatty acids from dietary sugar, establishing a symbiotic relationship crucial to many body functions previously thought to depend solely on fiber.

Stanford Medicine experts report that while nearly three in five American adults take supplements, most offer no scientifically proven benefit, and some can be harmful, with better absorption from whole foods.

A study published in Nature Medicine found that older adults taking a daily multivitamin showed slower biological aging—approximately 4 months less than those who didn't take supplements.

Research found that higher levels of the minerals copper and manganese in pregnant women were associated with lower blood pressure and reduced risk of developing hypertension decades later.

A large study of over 200,000 individuals followed for more than 30 years found that higher intake of plant-based oils, especially soybean, canola, and olive oil, was associated with better health outcomes.

Higher levels of the minerals copper and manganese in pregnant women were associated with lower blood pressure and reduced risk of developing hypertension decades later.

Analysis of 2,877 centenarians found approximately 10-12% used dietary supplements, with calcium, protein, and multivitamins being most common, suggesting modest supplement use in longevity populations.

A study published in Nature Medicine found that older adults taking a daily multivitamin showed slower biological aging—approximately 4 months less than those who didn't take supplements.

Recent research reveals that high doses of antioxidants, often considered harmless or beneficial, may actually impact future generations, as demonstrated in studies with male mice.

A large study of over 200,000 individuals followed for 30+ years found that higher intake of plant-based oils, especially soybean, canola, and olive oil, was associated with better health.

Higher copper and manganese levels in pregnant women were associated with lower blood pressure and reduced hypertension risk decades later, based on long-term cohort data. This highlights prenatal mineral status for cardiovascular health implications.

The NIH Office of Dietary Supplements released a strategic plan outlining expanded research on vitamins, minerals, and supplements, fostering federal collaboration for evidence-based health insights applicable to public nutrition.

A randomized clinical trial tests five food supplements rich in fibers (psyllium, glucomannan, inulin), choline, and herbal extracts (artichoke, cumin, peppermint) combined with diet restriction in overweight adults, targeting body fat, visceral fat, lipids, and inflammation over eight weeks.

Analysis of over 200,000 participants followed for 30+ years showed higher intake of plant-based oils like soybean, canola, and olive reduced mortality risk compared to butter consumption. Replacing butter with plant oils offers practical dietary benefits for health.

A study in Nature Medicine found that older adults taking a daily multivitamin, such as Centrum Silver, experienced slower biological aging, equivalent to about four months less aging compared to placebo over three years. This suggests potential clinical benefits for physical and cognitive function in aging populations.

Higher copper and manganese in pregnant women associated with lower blood pressure and reduced hypertension risk decades later. Key for maternal nutrition and cardiovascular health.

A study found older adults taking daily multivitamins showed slower biological aging, about 4 months less than placebo, measured by DNA methylation clocks. Published in Nature Medicine with practical implications for longevity in seniors.

Analysis of 200,000+ people over 30 years shows higher plant oil intake (soybean, canola, olive) vs. butter linked to better health. Practical dietary shift for everyday wellness.

Randomized trial tests fiber blends (plantain, glucomannan), herbals (artichoke, cumin), vitamins/minerals with calorie restriction on body fat, lipids, inflammation in overweight adults over 8 weeks. Outcomes include fat loss and metabolic improvements.

NIH Office of Dietary Supplements releases key research advances in vitamins, minerals, and supplements, informing practical health strategies. Includes strategic plan for 2025-2029 research.

Recent research reveals that high doses of antioxidants, often considered harmless, may have transgenerational effects, with male mice studies showing potential impacts on offspring.

A Nature Medicine study found that older adults taking daily multivitamins experienced biological aging approximately 4 months slower than non-users, suggesting potential longevity benefits.

A study found that higher levels of copper and manganese minerals in pregnant women were associated with lower blood pressure and reduced hypertension risk decades later in offspring.

A large 30-year study of over 200,000 individuals found that higher intake of plant-based oils, especially soybean, canola, and olive oil, was associated with improved health compared to butter consumption.

Analysis of 2,877 Chinese centenarians found 10.7% of females and 12.3% of males used dietary supplements, primarily calcium, protein, and multivitamins, with median use duration of 2-10 years.

Higher levels of copper and manganese minerals in pregnant women were associated with lower blood pressure and reduced risk of hypertension decades later in offspring.

A new study reveals that high doses of antioxidants may actually impact future generations, challenging the common assumption that antioxidants are harmless or universally beneficial.

Research published in Nature Medicine found that older adults taking daily multivitamins biologically aged 3-5 months slower than those who did not take supplements.

A large 30-year study of over 200,000 individuals found that higher intake of plant-based oils, especially soybean, canola, and olive oil, was associated with better health outcomes.

A new discovery reveals that gut microbes produce short-chain fatty acids crucial to body functions by metabolizing both dietary fiber and sugar from the gut.

Analysis of over 200,000 individuals followed for more than 30 years showed higher intake of plant-based oils like soybean, canola, and olive oil associated with reduced mortality risk.

The NIH Office of Dietary Supplements published its Strategic Plan for 2025–2029, outlining priorities for advancing dietary supplement research and federal collaboration.

The AREDS2 formula with lutein and zeaxanthin instead of beta-carotene better reduces advanced AMD progression risk and avoids beta-carotene's lung cancer risk.

During 2017–2018, 57.6% of US adults aged 20+ used any dietary supplement, with higher use among women and increasing with age; multivitamins, vitamin D, and omega-3 were most common.

Researchers at Mass General Brigham found that older adults taking a daily multivitamin exhibited slower biological aging, equivalent to about 4 months less aging compared to those who did not take supplements.

A randomized double-blind trial tests five fiber-rich supplements with diet restriction in overweight adults, targeting improvements in lipids, blood pressure, inflammation, and body fat over eight weeks.

A randomized trial in the COSMOS study found that daily multivitamins for two years slowed epigenetic aging by 0.113-0.214 years per year on biological clocks in adults around age 70, with benefits for inflammation and cognition. This could reduce cancer risk by 3-7% over 10 years.

Higher copper and manganese levels in pregnant women associated with reduced blood pressure and hypertension risk decades later in midlife.

The AREDS2 formula, replacing beta-carotene with lutein and zeaxanthin, reduces lung cancer risk and is more effective at slowing age-related macular degeneration progression.

Combining omega-3 (1g+ for women), vitamin D, and strength training slowed biological aging by 3.8 months and reduced prefrailty by 40%, with omega-3 dose effects varying by gender.

Older adults taking a daily multivitamin showed slower biological aging, about four months less than those who didn't, per Mass General Brigham study published in Nature Medicine.

Research from Mass General Brigham found older adults on daily multivitamins biologically aged slower by roughly 4 months compared to non-users.

Higher copper and manganese in pregnant women associated with lower blood pressure and reduced hypertension risk decades later.

Large study of 200,000+ people over 30 years shows higher plant-based oils (soybean, canola, olive) intake linked to better health vs. butter.

Gut microbes fed sugar from hosts produce short-chain fatty acids essential for body functions, revealing new symbiotic role beyond fiber.

Higher levels of copper and manganese minerals in pregnant women were associated with lower blood pressure and reduced risk of developing hypertension decades later in offspring.

Research revealed that gut microbes produce short-chain fatty acids from dietary sugar, establishing a symbiotic relationship crucial to many body functions beyond fiber fermentation.

A new clinical trial suggests a 5-day fasting-mimicking diet could offer real relief for Crohn's disease, a condition that has long lacked clear dietary guidance.

Researchers at Mass General Brigham found that older adults taking a daily multivitamin showed approximately 4 months slower biological aging compared to those who did not take supplements.

A 30-year study of over 200,000 individuals found that higher intake of plant-based oils, especially soybean, canola, and olive oil, was linked to better health compared to butter consumption.

Researchers at Mass General Brigham found that older adults taking a daily multivitamin showed slower biological aging—approximately 4 months less than those who didn't take supplements.

A 2026 review in Nutrients journal found vitamin D influences over 1,000 genes and is essential for skeletal health and may shape immune, metabolic, and neurodevelopmental pathways during early life, though non-skeletal benefits need stronger human evidence.

The FDA approved Foundayo, a GLP-1 receptor agonist tablet for weight management, marking the fastest approval of a new molecular entity since 2002 and the first NME under the Commissioner's National Priority Voucher program.

Stanford Medicine nutrition experts report that while nearly 60% of American adults take supplements, most offer no scientifically proven benefit and some can be harmful, with the supplement market largely unregulated compared to pharmaceuticals.

A large NIH clinical trial found that omega-3 fatty acid supplements from fish oil did not slow cognitive decline in older persons, despite some observational evidence suggesting dietary omega-3s may protect brain health.

A comprehensive review in Nutrients found vitamin D is essential for skeletal health and may influence immune, metabolic, and neurodevelopmental pathways during early life, though non-skeletal benefits in humans need stronger evidence.

A sweeping review of nearly 20 studies found healthier diets linked to fewer depressive symptoms in teens, while poor eating habits associated with increased mental health concerns.

Observational studies of over 35,000 mother-offspring pairs found low maternal vitamin D levels associated with higher risks of small-for-gestational-age infants and lower birth weights.

Meta-analyses of over 48,000 participants showed vitamin D supplementation at 400-1,000 IU daily produced small reductions in acute respiratory tract infection risk, with age-dependent effects.

A Nature Medicine study found older adults taking daily multivitamins showed slower biological aging—approximately four months less than those who didn't take supplements.

FDA held a public meeting on March 27, 2026 to explore the regulatory scope of dietary supplement ingredients including proteins, enzymes, and microbials under DSHEA, with comment deadline of April 27, 2026.

Pasteurized Akkermansia muciniphila postbiotic demonstrated efficacy in reducing body weight and body fat in overweight and obese adults, with comparative studies showing benefits similar to Lactobacillus rhamnosus in randomized controlled trials.

The Office of Dietary Supplement (ODS) presented virtual seminars on dietary supplement research and related topics as part of the 2025-2026 seminar series.

2026 is anticipated to be the most impactful year for dietary supplements since the introduction of GMPs, with significant regulatory changes expected for the industry.

Increased daylight in summer supports serotonin production and vitamin D synthesis, improving mood and energy levels, while longer daylight hours regulate circadian rhythms and encourage outdoor activity and exercise.