Beta
Aminohippuric acid
medication Under reviewAminohippuric acid, also known as para-aminohippuric acid (PAH), is a derivative of hippuric acid with an amino group attached to the para position of the benzene ring. It is primarily recognized in medical diagnostics for assessing renal function, particularly as a marker for effective renal plasma flow due to its complete extraction by the kidneys during a single pass through the renal vasculature. PAH is administered intravenously and actively secreted by the proximal tubules, allowing measurement of renal blood flow independent of glomerular filtration.
Research summary
Scientific evidence on aminohippuric acid as a supplement is extremely limited, with its primary use confined to clinical diagnostics for evaluating kidney function in healthy subjects rather than for therapeutic supplementation. No studies demonstrate benefits for general health, performance, or longevity in healthy humans, and it is not marketed or studied as a dietary supplement. Research consensus views it solely as a diagnostic tool, with no established role in supplementation.
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