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Beta

B-Complex

supplement

B-Complex vitamins support energy and brain function.

Reported Benefits

No reports yet

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Systematic Review A structured review of all available research on a topic. Considered the strongest form of evidence overview. Moderate Evidence Single RCT or well-designed observational studies. Solid with some limitations.

How B Vitamins Can Affect Brain and Heart Health

Tufts Medicine • 2024

Rosenberg and Mason (Tufts University)

Review of clinical evidence including the Framingham Heart Study and trials such as VITACOG and FACT showing that B-vitamin supplementation can slow brain shrinkage and improve cognitive performance in those at risk, with particular promise for B6 in reducing chronic inflammation.

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Systematic Review A structured review of all available research on a topic. Considered the strongest form of evidence overview. Strong Evidence Multiple RCTs or meta-analyses — controlled, repeatable, peer-reviewed.

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

Nutrients • 2015

Multiple authors

Comprehensive review demonstrating that B-Complex vitamins support brain function through energy production and homocysteine metabolism. Dose-ranging studies show bioavailability increases persist well above the RDA, with folic acid at 800 µg/day and B12 at up to 1000 µg/day producing significant reductions in homocysteine levels and improvements in endothelial function in healthy subjects.

No reports yet

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Dietary Vitamin B Complex: Orchestration in Human Nutrition

PMC • 2022

Multiple authors

Review demonstrating that higher intake of B vitamins in healthy elderly populations is associated with prevention of aging-related problems, particularly those related to inflammation.

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

Nutrients • 2015

Multiple authors

No reports yet

Be the first to report this effect and help the community.

Add B-complex to your stack to report effects

Dietary Vitamin B Complex: Orchestration in Human Nutrition

PMC • 2022

Multiple authors

Review demonstrating that higher intake of B vitamins in healthy elderly populations is associated with prevention of aging-related problems, particularly those related to inflammation.

No reports yet

Be the first to report this effect and help the community.

Add B-complex to your stack to report effects

How B Vitamins Can Affect Brain and Heart Health

Tufts Medicine • 2024

Rosenberg and Mason (Tufts University)

Read study

No reports yet

Be the first to report this effect and help the community.

Add B-complex to your stack to report effects

How B Vitamins Can Affect Brain and Heart Health

Tufts Medicine • 2024

Rosenberg and Mason (Tufts University)

Read study

No reports yet

Be the first to report this effect and help the community.

Add B-complex to your stack to report effects

Dietary Vitamin B Complex: Orchestration in Human Nutrition

PMC • 2022

Multiple authors

Review demonstrating that higher intake of B vitamins in healthy elderly populations is associated with prevention of aging-related problems, particularly those related to inflammation.

No side effects tracked yet

No side effects have been reported by studies or users for this habit yet.

Related health conditions

Research showing how this habit affects specific health conditions. Always consult healthcare professionals.

May Help With

Elevated LDL cholesterol or total cholesterol levels

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

Nutrients • 2015

Multiple authors

Research (3 studies)

Systematic Review A structured review of all available research on a topic. Considered the strongest form of evidence overview.

How B Vitamins Can Affect Brain and Heart Health

Tufts Medicine • 2024

Rosenberg and Mason (Tufts University)

Read study

Systematic Review A structured review of all available research on a topic. Considered the strongest form of evidence overview.

Dietary Vitamin B Complex: Orchestration in Human Nutrition

PMC • 2022

Multiple authors

Review demonstrating that higher intake of B vitamins in healthy elderly populations is associated with prevention of aging-related problems, particularly those related to inflammation.

Systematic Review A structured review of all available research on a topic. Considered the strongest form of evidence overview.

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

Nutrients • 2015

Multiple authors

Community updates

No updates yet for this supplement.

Be the first to share your experience!

At a glance

Users tracking 2

Linked studies 3

Researched benefits 6

Side effects noted 0

Notable users

@bryanjohnson

Morning

@rhonda_patrick

Daily

Evidence tiers

Each benefit or side effect is rated by how much evidence exists — studies + community reports combined.

🏆 Gold

5+ studies and 500+ community reports. The most well-established evidence available.

🥈 Silver

2+ studies and 200+ community reports. Solid, reproducible evidence with meaningful community backing.

🥉 Bronze

1+ study or 100+ community reports. Early research with growing support.

🔬 Emerging

50+ community reports but no formal studies yet. Patterns observed by users, awaiting research.

💬 Anecdotal

Fewer than 50 reports, no formal studies. Very early or individual observations only.

Tiers are auto-calculated from linked studies and community reports. Always consult a healthcare professional before changing your routine.

Evidence levels

Each linked study is rated by the quality of its research methodology, independent of quantity.

Strong evidence

Multiple RCTs or meta-analyses. The gold standard of clinical research — controlled, repeatable, and peer-reviewed.

Moderate evidence

Single RCT or multiple well-designed observational studies. Solid methodology with some limitations.

Preliminary

Early-stage research — small trials, pilot studies, or limited data. Promising but not yet conclusive.

Weak evidence

Very limited formal research — animal studies, case reports, or mostly user observations.

Evidence levels are assessed per study by our research team. A single strong study can still have limited reach — see evidence tiers for the full picture.

B-Complex

Reported Benefits

Energy levels

How B Vitamins Can Affect Brain and Heart Health

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

Heart health

Dietary Vitamin B Complex: Orchestration in Human Nutrition

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

Cognitive function

Dietary Vitamin B Complex: Orchestration in Human Nutrition

Physical performance

How B Vitamins Can Affect Brain and Heart Health

Endurance

How B Vitamins Can Affect Brain and Heart Health

Inflammation

Dietary Vitamin B Complex: Orchestration in Human Nutrition

No side effects tracked yet

Related health conditions

May Help With

High Cholesterol

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

Research (3 studies)

How B Vitamins Can Affect Brain and Heart Health

Dietary Vitamin B Complex: Orchestration in Human Nutrition

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

Community updates

At a glance

Notable users