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Benzodiazepines (diazepam, lorazepam, etc.)
medication Under reviewBenzodiazepines, such as diazepam and lorazepam, are a class of psychoactive medications that enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor in the central nervous system. This action increases inhibitory signaling, leading to sedative, anxiolytic, muscle relaxant, and anticonvulsant effects. They are commonly prescribed for short-term management of acute conditions requiring rapid calming or seizure control.
Research summary
Scientific evidence from studies in healthy human subjects is limited, primarily focusing on comparisons of efficacy and safety between specific benzodiazepines like lorazepam and diazepam in controlled settings or their acute effects on cognition and anxiety. Research consensus indicates they effectively reduce anxiety and impair cognitive processes such as memory encoding in healthy individuals, but long-term use is not studied in this population due to risks of dependence.
Reported Benefits
No reports yet
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Add Benzodiazepines (diazepam, lorazepam, etc.) to your stack to report effects
Effects of lorazepam and diazepam on conscious and automatic memory processes.
Not specified
A comparison of lorazepam, diazepam and placebo in the treatment of anxiety states.
Various
No reports yet
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Add Benzodiazepines (diazepam, lorazepam, etc.) to your stack to report effects
Effects of lorazepam and diazepam on conscious and automatic memory processes.
Not specified
Reported Side Effects
No reports yet
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Add Benzodiazepines (diazepam, lorazepam, etc.) to your stack to report effects
Effectiveness and safety of midazolam versus lorazepam for pediatric status epilepticus: A systematic review and meta-analysis.
Chamberlain et al.
No reports yet
Be the first to report this effect and help the community.
Add Benzodiazepines (diazepam, lorazepam, etc.) to your stack to report effects
Effects of lorazepam and diazepam on conscious and automatic memory processes.
Not specified
No reports yet
Be the first to report this effect and help the community.
Add Benzodiazepines (diazepam, lorazepam, etc.) to your stack to report effects
Effectiveness and safety of midazolam versus lorazepam for pediatric status epilepticus: A systematic review and meta-analysis.
Chamberlain et al.
Research (3 studies)
Effects of lorazepam and diazepam on conscious and automatic memory processes.
Not specified
Effectiveness and safety of midazolam versus lorazepam for pediatric status epilepticus: A systematic review and meta-analysis.
Chamberlain et al.
A comparison of lorazepam, diazepam and placebo in the treatment of anxiety states.
Various
Community updates
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