Doseloop Beta

Chlorpromazine

medication Under review

A first-generation antipsychotic medication primarily used to treat psychotic disorders such as schizophrenia and bipolar disorder.

Research summary

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Scientific evidence on chlorpromazine in healthy human subjects is extremely limited, with most research focused on patient populations like those with schizophrenia, where low-quality studies suggest benefits in reducing relapse and improving symptoms. One randomized controlled trial in healthy volunteers examined its impact on esophageal sensitivity, finding potential modulation of pain thresholds via multimodal stimulation tests. Overall consensus indicates insufficient high-quality data for healthy humans, emphasizing its role as a prescription drug rather than a supplement, with calls for better trials on key outcomes.

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