Beta
Cimetidine
medication Under reviewA histamine H2 receptor antagonist that inhibits stomach acid production, used to treat heartburn, ulcers, and GERD.
Research summary
Scientific evidence primarily supports cimetidine's efficacy in managing peptic ulcers, gastroesophageal reflux, and gastric hypersecretion in humans, with consistent findings from controlled trials showing ulcer healing and symptom relief. Limited studies in healthy subjects demonstrate good tolerability at standard doses, though research on supplemental uses like immune modulation or dermatology often involves patients rather than healthy individuals, leaving gaps in data for non-medical applications. Consensus favors its short-term use for acid-related disorders due to proven acid suppression, but long-term safety and off-label benefits lack robust healthy human trials, with most anti-tumor or immunomodulatory effects derived from preclinical or diseased population studies.
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Cimetidine - StatPearls
Bolesta S, Khan R
Cimetidine: a review of its pharmacological properties and therapeutic efficacy in peptic ulcer disease.
Brogden RN, Heel RC, Speight TM, Avery GS
No reports yet
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Cimetidine - StatPearls
Bolesta S, Khan R
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Research (2 studies)
Cimetidine - StatPearls
Bolesta S, Khan R
Cimetidine: a review of its pharmacological properties and therapeutic efficacy in peptic ulcer disease.
Brogden RN, Heel RC, Speight TM, Avery GS
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