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Dicumarol
medication Under reviewAn anticoagulant medication that acts as a vitamin K antagonist to prevent blood clot formation.
Research summary
Scientific evidence on dicumarol in healthy humans is limited to mid-20th-century clinical studies focused on its anticoagulant effects and reversal by vitamin K compounds. These studies consistently demonstrate its ability to induce hypoprothrombinemia reliably, with effective neutralization by specific vitamin K forms, establishing it as a prototype oral anticoagulant. No recent human trials exist, and research consensus views it as obsolete for routine use due to variable absorption and bleeding risks, though it informs current anticoagulant therapy.
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Studies on dicumarol in human beings; its neutralization by vitamin K1 oxide, menadione bisulfite, synkayvite and blood.
D F James, I L Bennett Jr
Studies on dicumarol in human beings; its neutralization by vitamin K1 oxide, menadione bisulfite, synkayvite and blood.
D F James, I L Bennett Jr
CLINICAL EXPERIENCES WITH DICUMAROL: REPORT OF 100 CASES
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No reports yet
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CLINICAL EXPERIENCES WITH DICUMAROL: REPORT OF 100 CASES
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No side effects tracked yet
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Research (3 studies)
Studies on dicumarol in human beings; its neutralization by vitamin K1 oxide, menadione bisulfite, synkayvite and blood.
D F James, I L Bennett Jr
Studies on dicumarol in human beings; its neutralization by vitamin K1 oxide, menadione bisulfite, synkayvite and blood.
D F James, I L Bennett Jr
CLINICAL EXPERIENCES WITH DICUMAROL: REPORT OF 100 CASES
Not specified
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