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Dipyridamole
medication Under reviewAn antiplatelet medication used to prevent blood clots and as a diagnostic agent in cardiac stress testing.
Research summary
Scientific evidence from randomized controlled trials in healthy human subjects shows that dipyridamole effectively inhibits platelet aggregation and reduces the formation of platelet thrombi ex vivo. Studies confirm its standalone activity and amplified effects when paired with aspirin, with reductions in aggregate size correlating to plasma levels. However, comprehensive reviews indicate limited additional benefits over aspirin alone in broader vascular event prevention, with ongoing needs for trials in primary prevention among healthy adults. The research consensus supports dipyridamole's role as an adjunct antiplatelet agent, but evidence specific to healthy humans is primarily from ex vivo models of thrombosis, with no strong data on long-term outcomes or other benefits like cognitive or metabolic enhancements.
Reported Benefits
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Effect of aspirin and dipyridamole on the interaction of human platelets with sub-endothelium: studies using citrated and native blood.
Not specified in abstract
Dipyridamole alone or combined with low-dose acetylsalicylic acid inhibits platelet aggregation in human whole blood ex vivo.
T H Müller, C A Su, H Weisenberger, R Brickl, G Nehmiz, W G Eisert
Cochrane review: dipyridamole for preventing major vascular events in patients with vascular disease.
Not specified in abstract
No reports yet
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Add Dipyridamole to your stack to report effects
Dipyridamole alone or combined with low-dose acetylsalicylic acid inhibits platelet aggregation in human whole blood ex vivo.
T H Müller, C A Su, H Weisenberger, R Brickl, G Nehmiz, W G Eisert
Cochrane review: dipyridamole for preventing major vascular events in patients with vascular disease.
Not specified in abstract
No side effects tracked yet
No side effects have been reported by studies or users for this habit yet.
Research (3 studies)
Cochrane review: dipyridamole for preventing major vascular events in patients with vascular disease.
Not specified in abstract
Dipyridamole alone or combined with low-dose acetylsalicylic acid inhibits platelet aggregation in human whole blood ex vivo.
T H Müller, C A Su, H Weisenberger, R Brickl, G Nehmiz, W G Eisert
Effect of aspirin and dipyridamole on the interaction of human platelets with sub-endothelium: studies using citrated and native blood.
Not specified in abstract
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