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Doxycycline
medication Under reviewA broad-spectrum tetracycline antibiotic used to treat various bacterial infections, acne, rosacea, and for malaria prophylaxis.
Research summary
Scientific evidence from systematic reviews and clinical trials indicates that doxycycline is generally well-tolerated for longer-term use of 8 weeks or more in healthy individuals, primarily studied for malaria prophylaxis and sexually transmitted infection prevention. Common mild side effects include gastrointestinal discomfort, skin reactions, and occasional neurological symptoms, with low rates of discontinuation. Research consensus supports its safety profile, though further studies are recommended to assess potential metabolic impacts like weight changes or blood pressure alterations.
Reported Side Effects
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Doxycycline - Assessment of Long-Term Health Effects of Malaria Prophylaxis
Institute of Medicine (US) Committee on the Assessment of Long-Term Health Effects of Antimalarial Drugs
Safety of Longer-Term Doxycycline Use: A Systematic Review and Meta-Analysis With Implications for Bacterial Sexually Transmitted Infection Chemoprophylaxis.
Stewart AG, et al.
No reports yet
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Doxycycline - Assessment of Long-Term Health Effects of Malaria Prophylaxis
Institute of Medicine (US) Committee on the Assessment of Long-Term Health Effects of Antimalarial Drugs
Research (2 studies)
Safety of Longer-Term Doxycycline Use: A Systematic Review and Meta-Analysis With Implications for Bacterial Sexually Transmitted Infection Chemoprophylaxis.
Stewart AG, et al.
Doxycycline - Assessment of Long-Term Health Effects of Malaria Prophylaxis
Institute of Medicine (US) Committee on the Assessment of Long-Term Health Effects of Antimalarial Drugs
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