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Eszopiclone
medication Under reviewA non-benzodiazepine hypnotic agent used for the treatment of insomnia.
Research summary
Multiple randomized controlled trials in healthy adults with insomnia have shown eszopiclone effectively reduces sleep latency, increases total sleep time, and enhances sleep quality and efficiency compared to placebo. These benefits persist over periods up to six months, with moderate effect sizes on sleep onset and maintenance, though some attenuation may occur with prolonged use. Evidence from systematic reviews supports its efficacy and tolerability, with no major safety concerns when used as recommended in healthy populations. Adverse events are generally mild, and studies indicate low risk of dependence or rebound insomnia upon discontinuation in healthy subjects. However, research primarily focuses on insomnia patients rather than completely healthy individuals without sleep complaints, limiting direct applicability to asymptomatic populations.
Reported Benefits
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Eszopiclone, a nonbenzodiazepine sedative-hypnotic agent for the treatment of transient and chronic insomnia.
Zammit GK
Eszopiclone (Lunesta): a new nonbenzodiazepine hypnotic agent.
Hedner J, et al.
Evidence-based pharmacological interventions for insomnia: a systematic review on the effects of eszopiclone on insomnia comorbid with mental disturbances.
Harsora P, Kessmann J
No reports yet
Be the first to report this effect and help the community.
Add Eszopiclone to your stack to report effects
Eszopiclone, a nonbenzodiazepine sedative-hypnotic agent for the treatment of transient and chronic insomnia.
Zammit GK
Eszopiclone (Lunesta): a new nonbenzodiazepine hypnotic agent.
Hedner J, et al.
Evidence-based pharmacological interventions for insomnia: a systematic review on the effects of eszopiclone on insomnia comorbid with mental disturbances.
Harsora P, Kessmann J
No side effects tracked yet
No side effects have been reported by studies or users for this habit yet.
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Help With
Difficulty falling asleep, staying asleep, or waking too early
Eszopiclone (Lunesta): a new nonbenzodiazepine hypnotic agent.
Hedner J, et al.
Eszopiclone, a nonbenzodiazepine sedative-hypnotic agent for the treatment of transient and chronic insomnia.
Zammit GK
Evidence-based pharmacological interventions for insomnia: a systematic review on the effects of eszopiclone on insomnia comorbid with mental disturbances.
Harsora P, Kessmann J
Research (3 studies)
Evidence-based pharmacological interventions for insomnia: a systematic review on the effects of eszopiclone on insomnia comorbid with mental disturbances.
Harsora P, Kessmann J
Eszopiclone, a nonbenzodiazepine sedative-hypnotic agent for the treatment of transient and chronic insomnia.
Zammit GK
Eszopiclone (Lunesta): a new nonbenzodiazepine hypnotic agent.
Hedner J, et al.
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