Beta
Insulin Regular Human
medication Under reviewA short-acting form of insulin used to control blood sugar levels in people with diabetes.
Research summary
In healthy human volunteers, acute infusion of regular human insulin has been used primarily as a physiological tool to study insulin’s effects on glucose metabolism, vascular function, and intermediary metabolism. These studies demonstrate that regular human insulin acutely enhances insulin-stimulated glucose uptake, suppresses circulating free fatty acids, and improves endothelium-dependent vasodilation, indicating beneficial short-term effects on vascular and metabolic function in the context of normal physiology. There is no research or clinical guideline support for the use of Insulin Regular Human as a supplement in healthy, non-diabetic individuals. All major research and regulatory frameworks treat it as a prescription medication for treating diabetes and related dysglycemic states. In healthy subjects, the overriding concern is the risk of hypoglycemia, which can be severe or life-threatening; therefore, outside of tightly controlled research or specific medical indications, its use in healthy people is not recommended.
Reported Benefits
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Insulin infusion acutely suppresses plasma free fatty acids and modulates lipid metabolism in healthy humans
Jensen MD, Caruso M, Heiling V, Miles JM
Dose–response characteristics for suppression of hepatic glucose production by insulin in normal man
Pilkis SJ, Rizza RA, Gerich JE
Acute metabolic and vascular effects of insulin in normal human subjects using euglycemic clamp methodology
DeFronzo RA, Tobin JD, Andres R
No reports yet
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Dose–response characteristics for suppression of hepatic glucose production by insulin in normal man
Pilkis SJ, Rizza RA, Gerich JE
Acute metabolic and vascular effects of insulin in normal human subjects using euglycemic clamp methodology
DeFronzo RA, Tobin JD, Andres R
No reports yet
Be the first to report this effect and help the community.
Add Insulin regular human to your stack to report effects
Dose–response characteristics for suppression of hepatic glucose production by insulin in normal man
Pilkis SJ, Rizza RA, Gerich JE
Acute metabolic and vascular effects of insulin in normal human subjects using euglycemic clamp methodology
DeFronzo RA, Tobin JD, Andres R
Reported Side Effects
No reports yet
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Hypoglycemic symptoms and cognitive performance during insulin-induced hypoglycemia in healthy volunteers
Veneman T, Mitrakou A, Mokan M, Cryer P, Gerich J
No reports yet
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Add Insulin regular human to your stack to report effects
Hypoglycemic symptoms and cognitive performance during insulin-induced hypoglycemia in healthy volunteers
Veneman T, Mitrakou A, Mokan M, Cryer P, Gerich J
Research (4 studies)
Hypoglycemic symptoms and cognitive performance during insulin-induced hypoglycemia in healthy volunteers
Veneman T, Mitrakou A, Mokan M, Cryer P, Gerich J
Insulin infusion acutely suppresses plasma free fatty acids and modulates lipid metabolism in healthy humans
Jensen MD, Caruso M, Heiling V, Miles JM
Dose–response characteristics for suppression of hepatic glucose production by insulin in normal man
Pilkis SJ, Rizza RA, Gerich JE
Acute metabolic and vascular effects of insulin in normal human subjects using euglycemic clamp methodology
DeFronzo RA, Tobin JD, Andres R
Community updates
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