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Loratadine
medication Under reviewA second-generation antihistamine used to treat symptoms of seasonal allergies and hives.
Research summary
Human clinical evidence shows that loratadine is effective for allergic rhinitis and chronic urticaria, with benefits demonstrated in placebo-controlled trials and broader clinical trial summaries. In healthy volunteer studies, standard doses were well tolerated, and pharmacokinetic studies showed predictable absorption and dose proportionality. The evidence base in healthy subjects supports symptomatic allergy relief as the primary benefit. There is no strong human evidence for broader general-health or performance effects, and available trials do not support use for unrelated indications such as bone pain prevention.
Reported Benefits
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Clinical Trials of CLARITIN Tablets in Allergic Rhinitis
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Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis.
Unspecified in search result
Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
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No reports yet
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Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis.
Unspecified in search result
Clinical Trials of CLARITIN Tablets in Allergic Rhinitis
Unspecified in search result
No reports yet
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Add Loratadine to your stack to report effects
Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
Unspecified in search result
No reports yet
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Add Loratadine to your stack to report effects
Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
Unspecified in search result
Reported Side Effects
No reports yet
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Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
Unspecified in search result
No reports yet
Be the first to report this effect and help the community.
Add Loratadine to your stack to report effects
Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
Unspecified in search result
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Help With
Immune system overreaction to environmental triggers
Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis.
Unspecified in search result
Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
Unspecified in search result
Clinical Trials of CLARITIN Tablets in Allergic Rhinitis
Unspecified in search result
Research (3 studies)
Clinical Trials of CLARITIN Tablets in Allergic Rhinitis
Unspecified in search result
Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
Unspecified in search result
Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis.
Unspecified in search result
Community updates
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