Doseloop Beta

Maralixibat

medication Under review

An ileal bile acid transporter (IBAT) inhibitor used to treat itching caused by Alagille syndrome and progressive familial intrahepatic cholestasis.

Research summary

AI-Generated Content: This summary was created by AI and may contain errors. Always verify with peer-reviewed sources.

Scientific evidence for maralixibat centers on its use in pediatric populations with cholestatic liver diseases like Alagille syndrome and progressive familial intrahepatic cholestasis, where it demonstrates reductions in pruritus severity and serum bile acids. No studies were identified involving healthy human subjects, limiting applicability to general wellness or supplementation in healthy individuals. Research consensus supports its safety and tolerability in diseased populations, with minor gastrointestinal side effects reported.

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