Minerals

In adults from a rural region with prevalent micronutrient deficiencies, long-term multivitamin/mineral supplementation modestly reduced total cancer incidence and all-cause mortality in men but not women, without appreciable effects on cardiovascular mortality.

Across large randomized trials in predominantly healthy adults, multivitamin/mineral supplementation did not meaningfully reduce risks of cardiovascular events, stroke, or overall mortality, though some trials reported modest reductions in total cancer incidence in specific subgroups.

In a large cohort of generally healthy U.S. adults followed for up to 27 years, daily multivitamin use was not associated with lower all-cause mortality or mortality from heart disease, cancer, or cerebrovascular disease compared with nonuse.

In a cross-sectional survey of healthy U.S. adults, multivitamin/mineral users reported better overall self-rated health than nonusers, but objective measures showed no clear differences in psychological, physical, or functional health outcomes.

This systematic review of randomized controlled trials and cohort studies in generally healthy adults found that vitamin and mineral supplementation, including multivitamins, yielded little or no benefit for preventing cardiovascular disease, cancer, or death, although multivitamin use was associated with a small reduction in overall cancer incidence and lung cancer.

Across large randomized trials in predominantly healthy adults, multivitamin/mineral supplementation did not meaningfully reduce risks of cardiovascular events, stroke, or overall mortality, though some trials reported modest reductions in total cancer incidence in specific subgroups.

This systematic review of randomized controlled trials and cohort studies in generally healthy adults found that vitamin and mineral supplementation, including multivitamins, yielded little or no benefit for preventing cardiovascular disease, cancer, or death, although multivitamin use was associated with a small reduction in overall cancer incidence and lung cancer.

In adults from a rural region with prevalent micronutrient deficiencies, long-term multivitamin/mineral supplementation modestly reduced total cancer incidence and all-cause mortality in men but not women, without appreciable effects on cardiovascular mortality.

In 14,641 male physicians aged 50 years or older followed for a median of 11.2 years, a daily multivitamin modestly reduced total cancer incidence but did not significantly affect major cardiovascular events or all‑cause mortality compared with placebo.

In 14,641 male physicians aged 50 years or older followed for a median of 11.2 years, a daily multivitamin modestly reduced total cancer incidence but did not significantly affect major cardiovascular events or all‑cause mortality compared with placebo.

This systematic review of randomized controlled trials and cohort studies in generally healthy adults found that vitamin and mineral supplementation, including multivitamins, yielded little or no benefit for preventing cardiovascular disease, cancer, or death, although multivitamin use was associated with a small reduction in overall cancer incidence and lung cancer.

Reviewing randomized trials in generally healthy adults, the authors found that standard-dose multivitamins were usually well tolerated with only minor gastrointestinal symptoms, while high-dose single or combined vitamins and minerals were linked to increased risks such as hip fracture, hemorrhagic stroke, kidney stones, and certain cancers.

Reviewing randomized trials in generally healthy adults, the authors found that standard-dose multivitamins were usually well tolerated with only minor gastrointestinal symptoms, while high-dose single or combined vitamins and minerals were linked to increased risks such as hip fracture, hemorrhagic stroke, kidney stones, and certain cancers.

Reviewing randomized trials in generally healthy adults, the authors found that standard-dose multivitamins were usually well tolerated with only minor gastrointestinal symptoms, while high-dose single or combined vitamins and minerals were linked to increased risks such as hip fracture, hemorrhagic stroke, kidney stones, and certain cancers.