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Nifedipine
medication Under reviewA calcium channel blocker used to treat high blood pressure and angina.
Research summary
Scientific evidence on nifedipine in healthy human subjects is limited to pharmacokinetic and pharmacodynamic studies, which consistently show rapid absorption, dose-dependent cardiovascular effects like brief heart rate increases and blood pressure reductions, and good tolerability. No studies demonstrate benefits for longevity, performance, or other supplement-like applications in healthy adults; research focuses on drug kinetics rather than therapeutic gains. Bioequivalence trials confirm consistent safety profiles across formulations, with minor adverse effects like dizziness and headache occurring transiently. Overall consensus supports its pharmacological reliability but does not position it as a supplement for healthy individuals.
Reported Benefits
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Nifedipine: a potent inhibitor of contractions in the body of the human esophagus. Studies in healthy volunteers and patients with the nutcracker esophagus.
Not specified in abstract
Nifedipine: kinetics and dynamics in healthy subjects.
Not specified in abstract
Reported Side Effects
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Pharmacokinetics of Nifedipine-Sustained Release Tablets in Healthy Subjects After a Single Oral Administration: Bioequivalence Analysis and Food Effects.
Sumei Xu, Pingsheng Xu
No reports yet
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Pharmacokinetics of Nifedipine-Sustained Release Tablets in Healthy Subjects After a Single Oral Administration: Bioequivalence Analysis and Food Effects.
Sumei Xu, Pingsheng Xu
Research (3 studies)
Pharmacokinetics of Nifedipine-Sustained Release Tablets in Healthy Subjects After a Single Oral Administration: Bioequivalence Analysis and Food Effects.
Sumei Xu, Pingsheng Xu
Nifedipine: a potent inhibitor of contractions in the body of the human esophagus. Studies in healthy volunteers and patients with the nutcracker esophagus.
Not specified in abstract
Nifedipine: kinetics and dynamics in healthy subjects.
Not specified in abstract
Community updates
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