Beta
Quazepam
medication Under reviewA benzodiazepine medication used for the short-term treatment of insomnia.
Research summary
Human studies of quazepam are focused largely on adults with insomnia and healthy volunteers, rather than on general wellness applications. Placebo-controlled sleep laboratory and outpatient trials consistently show that quazepam at doses of 7.5–15 mg improves objective and subjective sleep measures, including sleep latency, total sleep time, number of awakenings, early morning awakening, and overall sleep quality. These effects have been demonstrated over short-term periods of several nights and in longer-term studies of up to four weeks and, in some trials, nearly a month of continuous use. In healthy human volunteers, single-dose pharmacodynamic studies indicate that quazepam produces minimal impairment of psychomotor performance, memory, and daytime alertness at standard hypnotic doses, especially when compared with shorter-acting benzodiazepines such as triazolam and non-benzodiazepine hypnotics like zolpidem. Nonetheless, sleep laboratory data in patients show that daytime sleepiness can occur with sustained use, reflecting its long half-life and active metabolites. Overall, the research supports quazepam as an effective hypnotic for insomnia with a relatively favorable cognitive and performance profile at therapeutic doses, but with recognized risks of sedation, tolerance, and dependence typical of benzodiazepine-class drugs.
Reported Benefits
No reports yet
Be the first to report this effect and help the community.
Add Quazepam to your stack to report effects
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
Roehrs T, Zorick F, Conway W, et al.
Short-term study of quazepam 15 milligrams in the treatment of insomnia.
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
Quazepam and flurazepam: long-term use and extended withdrawal
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
A clinical study of quazepam in hospitalized patients with insomnia
Uhthoff HK, Brunet JA, Aggerwal A, Varin R
No reports yet
Be the first to report this effect and help the community.
Add Quazepam to your stack to report effects
A clinical study of quazepam in hospitalized patients with insomnia
Uhthoff HK, Brunet JA, Aggerwal A, Varin R
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
Roehrs T, Zorick F, Conway W, et al.
Short-term study of quazepam 15 milligrams in the treatment of insomnia.
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
Quazepam and flurazepam: long-term use and extended withdrawal
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
No reports yet
Be the first to report this effect and help the community.
Add Quazepam to your stack to report effects
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
Roehrs T, Zorick F, Conway W, et al.
Short-term study of quazepam 15 milligrams in the treatment of insomnia.
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
Quazepam and flurazepam: long-term use and extended withdrawal
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
A clinical study of quazepam in hospitalized patients with insomnia
Uhthoff HK, Brunet JA, Aggerwal A, Varin R
Reported Side Effects
No reports yet
Be the first to report this effect and help the community.
Add Quazepam to your stack to report effects
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
Roehrs T, Zorick F, Conway W, et al.
Quazepam and flurazepam: long-term use and extended withdrawal
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
No reports yet
Be the first to report this effect and help the community.
Add Quazepam to your stack to report effects
Quazepam and flurazepam: long-term use and extended withdrawal
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
No reports yet
Be the first to report this effect and help the community.
Add Quazepam to your stack to report effects
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
Roehrs T, Zorick F, Conway W, et al.
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Help With
Difficulty falling asleep, staying asleep, or waking too early
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
Roehrs T, Zorick F, Conway W, et al.
Short-term study of quazepam 15 milligrams in the treatment of insomnia.
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
Quazepam and flurazepam: long-term use and extended withdrawal
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
A clinical study of quazepam in hospitalized patients with insomnia
Uhthoff HK, Brunet JA, Aggerwal A, Varin R
May Worsen
Breathing repeatedly stops and starts during sleep
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
Roehrs T, Zorick F, Conway W, et al.
Research (4 studies)
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
Roehrs T, Zorick F, Conway W, et al.
Quazepam and flurazepam: long-term use and extended withdrawal
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
Short-term study of quazepam 15 milligrams in the treatment of insomnia.
Roehrs T, Zorick F, Wittig R, Conway W, Roth T
A clinical study of quazepam in hospitalized patients with insomnia
Uhthoff HK, Brunet JA, Aggerwal A, Varin R
Community updates
No updates yet for this supplement.
Be the first to share your experience!