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Rapamycin

medication

mTOR inhibitor used off-label for longevity. Prescription-only immunosuppressant that may extend lifespan and healthspan. Requires regular blood monitoring.

Reported Benefits

No reports yet

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Add Rapamycin to your stack to report effects

Preliminary Early or exploratory research not yet formally classified. Treat findings with caution. Weak Evidence Very limited formal research — animal studies, case reports, or user observations.

Rapamycin for Longevity & Aging: Potential Benefits and Risks

NOVOS Labs • 2024

Cites human studies showing reduced inflammation and improved immunity in aging humans, alongside cardiovascular risk factor reductions, emphasizing promise despite predominant animal data.

Read study

RCT Randomised Controlled Trial (RCT) — participants are randomly assigned to treatment or control groups, minimising bias. Gold standard for proving cause and effect. Moderate Evidence Single RCT or well-designed observational studies. Solid with some limitations.

Low-Dose Rapamycin Improves Muscle Mass and Well-Being in Aging Adults

Aging • 2025 • n=114

Mauricio Moel, Stefanie L. Morgan et al.

In a 48-week randomized, double-blind, placebo-controlled trial of 114 healthy adults aged 50-85, weekly 5mg or 10mg rapamycin increased lean muscle mass and reduced pain in women, improved emotional well-being and general health at 5mg, and was well-tolerated with only mild gastrointestinal issues.

Read study

No reports yet

Be the first to report this effect and help the community.

Add Rapamycin to your stack to report effects

Preliminary Early or exploratory research not yet formally classified. Treat findings with caution. Weak Evidence Very limited formal research — animal studies, case reports, or user observations.

Rapamycin for Longevity & Aging: Potential Benefits and Risks

NOVOS Labs • 2024

Cites human studies showing reduced inflammation and improved immunity in aging humans, alongside cardiovascular risk factor reductions, emphasizing promise despite predominant animal data.

Read study

No reports yet

Be the first to report this effect and help the community.

Add Rapamycin to your stack to report effects

Preliminary Early or exploratory research not yet formally classified. Treat findings with caution. Weak Evidence Very limited formal research — animal studies, case reports, or user observations.

Rapamycin for Longevity & Aging: Potential Benefits and Risks

NOVOS Labs • 2024

Cites human studies showing reduced inflammation and improved immunity in aging humans, alongside cardiovascular risk factor reductions, emphasizing promise despite predominant animal data.

Read study

No side effects tracked yet

No side effects have been reported by studies or users for this habit yet.

Research (2 studies)

RCT Randomised Controlled Trial (RCT) — participants are randomly assigned to treatment or control groups, minimising bias. Gold standard for proving cause and effect.

Low-Dose Rapamycin Improves Muscle Mass and Well-Being in Aging Adults

Aging • 2025 • n=114

Mauricio Moel, Stefanie L. Morgan et al.

Read study

Preliminary Early or exploratory research not yet formally classified. Treat findings with caution.

Rapamycin for Longevity & Aging: Potential Benefits and Risks

NOVOS Labs • 2024

Cites human studies showing reduced inflammation and improved immunity in aging humans, alongside cardiovascular risk factor reductions, emphasizing promise despite predominant animal data.

Read study

Community updates

No updates yet for this supplement.

Be the first to share your experience!

At a glance

Users tracking 0

Linked studies 2

Researched benefits 3

Side effects noted 0

Evidence tiers

Each benefit or side effect is rated by how much evidence exists — studies + community reports combined.

🏆 Gold

5+ studies and 500+ community reports. The most well-established evidence available.

🥈 Silver

2+ studies and 200+ community reports. Solid, reproducible evidence with meaningful community backing.

🥉 Bronze

1+ study or 100+ community reports. Early research with growing support.

🔬 Emerging

50+ community reports but no formal studies yet. Patterns observed by users, awaiting research.

💬 Anecdotal

Fewer than 50 reports, no formal studies. Very early or individual observations only.

Tiers are auto-calculated from linked studies and community reports. Always consult a healthcare professional before changing your routine.

Evidence levels

Each linked study is rated by the quality of its research methodology, independent of quantity.

Strong evidence

Multiple RCTs or meta-analyses. The gold standard of clinical research — controlled, repeatable, and peer-reviewed.

Moderate evidence

Single RCT or multiple well-designed observational studies. Solid methodology with some limitations.

Preliminary

Early-stage research — small trials, pilot studies, or limited data. Promising but not yet conclusive.

Weak evidence

Very limited formal research — animal studies, case reports, or mostly user observations.

Evidence levels are assessed per study by our research team. A single strong study can still have limited reach — see evidence tiers for the full picture.

Rapamycin

Reported Benefits

Longevity

Rapamycin for Longevity & Aging: Potential Benefits and Risks

Low-Dose Rapamycin Improves Muscle Mass and Well-Being in Aging Adults

Inflammation

Rapamycin for Longevity & Aging: Potential Benefits and Risks

Immune function

Rapamycin for Longevity & Aging: Potential Benefits and Risks

No side effects tracked yet

Research (2 studies)

Low-Dose Rapamycin Improves Muscle Mass and Well-Being in Aging Adults

Rapamycin for Longevity & Aging: Potential Benefits and Risks

Community updates

At a glance