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Tamoxifen
medication Under reviewA selective estrogen receptor modulator (SERM) medication used to treat and prevent hormone receptor-positive breast cancer.
Research summary
Scientific evidence from large trials shows tamoxifen reduces breast cancer risk and recurrence in high-risk healthy postmenopausal women, with benefits persisting over 15 years. The STAR trial confirmed its efficacy comparable to raloxifene in preventing invasive breast cancer, though with higher rates of certain side effects like uterine cancer and blood clots. Consensus supports its use for prevention in select healthy at-risk populations, balanced against risks, with no broad evidence for other health benefits in healthy humans.
Reported Benefits
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Long-Term Data from 20 Trials Confirm Tamoxifen's Long-Lasting Benefit
Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
The Study of Tamoxifen and Raloxifene (STAR) Trial Results
National Surgical Adjuvant Breast and Bowel Project (NSABP)
Reported Side Effects
No reports yet
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Add Tamoxifen to your stack to report effects
The Study of Tamoxifen and Raloxifene (STAR) Trial Results
National Surgical Adjuvant Breast and Bowel Project (NSABP)
No reports yet
Be the first to report this effect and help the community.
Add Tamoxifen to your stack to report effects
The Study of Tamoxifen and Raloxifene (STAR) Trial Results
National Surgical Adjuvant Breast and Bowel Project (NSABP)
Research (2 studies)
Long-Term Data from 20 Trials Confirm Tamoxifen's Long-Lasting Benefit
Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
The Study of Tamoxifen and Raloxifene (STAR) Trial Results
National Surgical Adjuvant Breast and Bowel Project (NSABP)
Community updates
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