Doseloop Beta

Temazepam

medication Under review

A benzodiazepine medication used for the short-term treatment of severe or debilitating insomnia.

Research summary

AI-Generated Content: This summary was created by AI and may contain errors. Always verify with peer-reviewed sources.

Scientific evidence from randomized controlled trials and polysomnography studies in healthy humans demonstrates that temazepam effectively reduces sleep latency and increases total sleep time, as measured both objectively and subjectively. Comparisons with other hypnotics like zolpidem show temazepam suppresses slow-wave sleep activity, distinguishing its EEG profile. Individual variability exists, with N-of-1 trials indicating benefits in some frequent users but not others, supporting personalized assessment for efficacy. Overall consensus supports temazepam as a short-term sleep aid with moderate evidence for improving sleep parameters in healthy adults, though long-term use is discouraged due to potential adverse effects observed in surveillance data.

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Research (4 studies)

RCT

Temazepam - StatPearls

StatPearls - NCBI Bookshelf • 2023

Not specified in excerpt

RCT

Randomised clinical trial of the effects of prolonged-release melatonin, temazepam and zolpidem on slow-wave activity during sleep in healthy people.

Journal of Psychopharmacology • 2015 • n=16

Not specified in excerpt

RCT

Efficacy of temazepam in frequent users: a series of N-of-1 trials

Family Practice • 2005 • n=12

Not specified in excerpt

RCT

Evaluation of Temazepam as a Hypnotic

Pharmacotherapy • 1981

Mitler

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At a glance

Users tracking 0
Linked studies 4
Researched benefits 2
Side effects noted 1