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Terbinafine
medication Under reviewAn antifungal medication used to treat fungal infections of the skin and nails.
Research summary
Clinical evidence supports terbinafine's high efficacy in resolving dermatophyte infections in humans, with response rates often exceeding 80% in short-term treatments for skin infections and superior long-term outcomes for nail infections compared to alternatives like itraconazole. Safety is generally favorable, with mild adverse effects in a minority of patients and excellent tolerability across studies. While primarily studied in patients with fungal infections, bioequivalence trials confirm consistent pharmacokinetics in healthy volunteers.
Reported Benefits
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Oral terbinafine (Lamisil) in the short-term treatment of fungal infections of the skin: results of a post-marketing surveillance study.
Faergemann J
Efficacy and Safety of Terbinafine 500 mg Once Daily in Patients with Dermatophytosis
Bhatia A, et al.
Long-term Effectiveness of Treatment With Terbinafine vs Itraconazole in Onychomycosis
Bräutigam M, et al.
Reported Side Effects
No reports yet
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Oral terbinafine (Lamisil) in the short-term treatment of fungal infections of the skin: results of a post-marketing surveillance study.
Faergemann J
Efficacy and Safety of Terbinafine 500 mg Once Daily in Patients with Dermatophytosis
Bhatia A, et al.
Research (3 studies)
Efficacy and Safety of Terbinafine 500 mg Once Daily in Patients with Dermatophytosis
Bhatia A, et al.
Oral terbinafine (Lamisil) in the short-term treatment of fungal infections of the skin: results of a post-marketing surveillance study.
Faergemann J
Long-term Effectiveness of Treatment With Terbinafine vs Itraconazole in Onychomycosis
Bräutigam M, et al.
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