THC
supplement Under reviewTHC, or delta-9-tetrahydrocannabinol, is the primary psychoactive compound found in cannabis. It exerts its effects by binding to cannabinoid receptors CB1 and CB2 in the endocannabinoid system, modulating neurotransmitter release and influencing physiological processes such as pain perception, appetite, mood, and cognition. Synthetic forms like dronabinol and nabilone mimic these actions and are used pharmaceutically at low doses.
Research summary
Scientific evidence on THC in healthy humans is limited, primarily from acute dosing studies examining cognitive, physiological, and appetite effects. Low doses (1.5-10 mg) show tolerability with minimal adverse effects, though impairments in processing speed, sedation, and blood pressure changes occur. Consensus supports safety at low doses but highlights risks of psychoactivity and cognitive disruption with higher or chronic use.
Reported Benefits
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THC Improves Optic Nerve Blood Flow Without Psychoactive Effects
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THC Increases Food Consumption and Alters Appetite Hormones
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Reported Side Effects
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Acute Effects of THC on Mood, Sedation, and Cognitive Performance
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Acute Effects of THC on Mood, Sedation, and Cognitive Performance
Not specified in source
No reports yet
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Acute Effects of THC on Mood, Sedation, and Cognitive Performance
Not specified in source
Research (3 studies)
THC Improves Optic Nerve Blood Flow Without Psychoactive Effects
Not specified in source
THC Increases Food Consumption and Alters Appetite Hormones
Not specified in source
Acute Effects of THC on Mood, Sedation, and Cognitive Performance
Not specified in source
Community updates
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