Doseloop Beta

THC

supplement Under review

THC, or delta-9-tetrahydrocannabinol, is the primary psychoactive compound found in cannabis. It exerts its effects by binding to cannabinoid receptors CB1 and CB2 in the endocannabinoid system, modulating neurotransmitter release and influencing physiological processes such as pain perception, appetite, mood, and cognition. Synthetic forms like dronabinol and nabilone mimic these actions and are used pharmaceutically at low doses.

Research summary

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Scientific evidence on THC in healthy humans is limited, primarily from acute dosing studies examining cognitive, physiological, and appetite effects. Low doses (1.5-10 mg) show tolerability with minimal adverse effects, though impairments in processing speed, sedation, and blood pressure changes occur. Consensus supports safety at low doses but highlights risks of psychoactivity and cognitive disruption with higher or chronic use.

Reported Benefits

Reported Side Effects

Research (3 studies)

RCT

THC Improves Optic Nerve Blood Flow Without Psychoactive Effects

Not specified • 2020

Not specified in source

RCT

THC Increases Food Consumption and Alters Appetite Hormones

Not specified • 2019

Not specified in source

RCT

Acute Effects of THC on Mood, Sedation, and Cognitive Performance

Not specified • 2015 • n=11

Not specified in source

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At a glance

Users tracking 0
Linked studies 3
Researched benefits 2
Side effects noted 3